- Abstract -

The study was performed in a group of 50 urolithiasis cases in the County Clinical Emergency Hospital Timisoara, during the period 2009-2010. A randomly selected group A, including 30 CRF cases in pre-dialysis stage, and a control group B, of 20 cases without CRF, were studied. Patients were subjected to a standard general clinical and biological examination of the urinary apparatus and a dental examination for diagnostic purposes. The role of saliva in the formation of periodontal lesions and the presence of salivary and serum tartar as local favoring factor were comparatively monitored in the group with urolithiasis induced CRF (in pre-dialysis and dialysis stages) and in the group without CRF. Patients with CRF caused by urinary lithiasis were found with significant changes in the ionic composition of saliva with decreased Ca and increased phosphate concentrations and had a more alkaline saliva as compared to patients without CRF and this phenomenon is not entirely due to the urease synthesized by oral bacteria but it is also based upon other causes (e.g. the phosphate buffer system). In conclusion, by extrapolating these results, even though the observed changes do not represent the exclusive cause of oral and periodontal pathology, significantly more frequently in patients with urolithiasis induced CRF, they may contribute as a general favoring factor together with tartar as local favoring factor in the occurrence of this pathology.

Key words: urinary lithiasis, urinary lithiasis induced CRF, dental tartar, periodontal lesions.