Objective.
The objective of our
study was to determine the prevalence of methicillin
resistant S. aureus (MRSA) in ICU.
Method: We have evaluated 291 samples collected from
278 patients hospitalized in ICU's Clinical
Emergency County Hospital Timişoara, in the period
of March-June 2009.
Results:
From 271 positive samples (bronchoalveolar fluids,
wound secretions, urines, blood, peritoneal fluids,
catheter tips) we isolated 276 microbial strains
with nosocomial potential, from wich 69 were
Staphylococcus aureus strains.
Conclusions:
In the Intensive Care Unit, Staphylococcus aureus
was the second most frequent isolated pathogen,
after Klebsiella pneumoniae.
From 69 S. aureus strains, 30 were MRSA (43, 47%).
In this study MRSA strains exhibit coresistance
against kanamycin, gentamicin, tobramycin,
ciprofloxacin, erythromycin and
trimethoprim-sulphamethoxazole. We did not isolate
any strain with linezolid, vancomycin, teicoplanin
and fosfomycin or rifampicin resistance. These
remain the drugs of choice for serious
staphylococcal infections.
Key words:
nosocomial infections, resistance phenotype, MRSA