Medicine in evolution








- Abstract -

Objective. The objective of our study was to determine the prevalence of methicillin resistant S. aureus (MRSA) in ICU.
Method: We have evaluated 291 samples collected from 278 patients hospitalized in ICU's Clinical Emergency County Hospital Timişoara, in the period of March-June 2009.

Results: From 271 positive samples (bronchoalveolar fluids, wound secretions, urines, blood, peritoneal fluids, catheter tips) we isolated 276 microbial strains with nosocomial potential, from wich 69 were Staphylococcus aureus strains.

Conclusions: In the Intensive Care Unit, Staphylococcus aureus was the second most frequent isolated pathogen, after Klebsiella pneumoniae.
From 69 S. aureus strains, 30 were MRSA (43, 47%). In this study MRSA strains exhibit coresistance against kanamycin, gentamicin, tobramycin, ciprofloxacin, erythromycin and trimethoprim-sulphamethoxazole. We did not isolate any strain with linezolid, vancomycin, teicoplanin and fosfomycin or rifampicin resistance. These remain the drugs of choice for serious staphylococcal infections.

Key words: nosocomial infections, resistance phenotype, MRSA



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